Questions? Contact us.

sidebar-facebook

For drug information, click here.

Factor X deficiency, or Stuart-Prower factor deficiency, is a rare bleeding disorder caused by low blood levels of a protein called coagulation factor X. It affects about one person per million worldwide and can vary in severity. The most severe cases occur in childhood, although symptoms can begin at any age.

The disorder can cause bleeding from the nose, from the gums, and under the skin; blood in the urine; easy bruising; and abnormal bleeding after surgery or trauma. Women might have heavy or prolonged bleeding during menstruation or in childbirth, and they might have increased risk of pregnancy loss. Patients with lower levels of coagulation factor X tend to have more severe symptoms, which can include bleeding inside the skull, lungs, or gastrointestinal tract.

Factor X deficiency can be inherited or acquired.

  • The inherited form is caused by mutations in the F10 gene, which provides instructions for making coagulation factor X. These mutations can lead to Type 1 factor X deficiency, in which the blood doesn’t have enough coagulation factor X, or Type 2 factor X deficiency, in which the coagulation factor X doesn’t work.
  • The acquired form can be caused by other disorders, such as severe liver disease or systemic amyloidosis. It can be caused by certain drugs (such as medicines that prevent clotting) or by a deficiency of vitamin K.

Traditionally, factor X deficiency was treated with prothrombin complex concentrates, which carried the risk of blood clots. Today, factor X deficiency can be treated with Coagadex®, a purified factor X concentrate available through Diplomat Specialty Infusion Group.

Sources: Genetics Home Reference, Food and Drug Administration, National Hemophilia Foundation

Reference to a specific product, process, or service does not constitute an endorsement or recommendation by Diplomat Pharmacy Inc., and any such reference is provided for educational purposes only.

More information for:

Return to homepage

How We
Help

In-Home Care

We offer in-home services to make care more convenient for your patients and reduce the burden on caregivers. To help your patients maintain their independence, we provide in-home nurses and training for those who wish to self-administer treatments outside of a clinical setting.

Shipping

We do everything we can to ensure the right medications arrive on time in the right place. Diplomat coordinates with a third-party carrier to facilitate the delivery of your patient’s medication. No order is too complicated for us, and if we need further information, we will always reach out to you directly.

Education

At Diplomat, we want our patients to have everything they need to feel supported. That’s why we provide disease–state specific education materials to keep them and their loved ones informed.

Advocacy

We understand that navigating the complex health care system can be a burden. We try to lighten it by providing advocacy services that offer personalized help when patients need it. If your patient needs copay assistance, our funding team goes to work, helping connect them with the appropriate third-party organizations. We’re here for them every step of the way.

Products We Support

Programs


  • ACT10N logo

    With ACT10N, patients with factor X deficiency have access to a highly specialized infusion care program, complete with personal support, clinical care and monitoring.

  • REBUILD logo

    Physical therapy is key to comprehensive hemophilia management. REBUILD facilitates training and connections between hemophilia patients and their local physical therapists.

  • IMPACT logo

    A comprehensive in-home inhibitor management program, IMPACT helps families affected by hemophilia with inhibitor options, education and personal support.

Featured Technology

A mobile health care application for patients with hemophilia and related bleeding disorders. The app helps patients conveniently track their personal infusion records and bleeding event history, as well as share important injury and treatment information with members of their health care team.

Learn more

Contact

Sending a prescription?

If you are a licensed prescriber, send your completed enrollment form directly to us via fax or mail.

Fax toll-free: 877.588.8470

Diplomat
7167 E. Kemper Road
Cincinnati, OH 45249

Enrollment Forms

Join our Diplomat Specialty Infusion Group mailing list.

Return to homepage

How We
Help

In-Home Care

We offer in-home services to make care more convenient for patients and reduce the burden on caregivers. We are passionate about adherence and want our patients to have successful treatments; in-home care reduces costs and helps patients maintain independence.

Shipping

We do everything we can to ensure the right medications arrive on time in the right place. Diplomat coordinates with a third-party carrier to facilitate delivery per patient’s or prescriber’s instructions.

Education

At Diplomat, we want our patients to have everything they need to feel supported. That’s why we provide disease–state specific education materials to keep them and their loved ones informed.

Advocacy

We understand that navigating the complex health care system can be a burden. We try to lighten it by providing advocacy services that offer personalized help when patients need it. If necessary, our patients receive prior authorization and appeals assistance. Our benefits investigation team helps them every step of the way.

Products We Support

Featured Technology

A mobile health care application for patients with hemophilia and related bleeding disorders. The app helps patients conveniently track their personal infusion records and bleeding event history, as well as share important injury and treatment information with members of their health care team.

Learn more

Take the first step in partnering with us.

Return to homepage

How We
Help

In-Home Care

We offer in-home services to make care more convenient for patients and reduce the burden on caregivers. We are passionate about adherence and want our patients to have successful treatments; in-home care reduces costs and helps patients maintain independence.

Shipping

We do everything we can to ensure the right medications arrive on time in the right place. Diplomat coordinates with a third-party carrier to facilitate delivery per patient’s or prescriber’s instructions. We don’t let anything get between a patient and their treatment.

Education

At Diplomat, we want our patients to have everything they need to feel supported. That’s why we provide disease–state specific education materials to keep them and their loved ones informed.

Advocacy

We understand that navigating the complex health care system can be a burden. We try to lighten it by providing advocacy services that offer personalized help when patients need it. If necessary, our patients receive prior authorization and appeals assistance. Our benefits investigation team helps them every step of the way.

Products We Support

Featured Technology

A mobile health care application for patients with hemophilia and related bleeding disorders. The app helps patients conveniently track their personal infusion records and bleeding event history, as well as share important injury and treatment information with members of their health care team.

Learn more

Take the first step in partnering with us.

Return to homepage

How We
Help

In-Home Care

We offer in-home services to make care more convenient for patients and reduce the burden on caregivers. To help patients maintain independence, we provide in-home nurses and training for those who wish to self-administer treatments outside of a clinical setting.

Shipping

We do everything we can to ensure the right medications arrive on time in the right place. Diplomat coordinates with a third-party carrier to facilitate delivery according to your instructions or those of your doctor.

Education

At Diplomat, we want our patients to have everything they need to feel supported. That’s why we provide disease–state specific education materials to keep you and your loved ones informed.

Advocacy

We understand that navigating the complex health care system can be a burden. We try to lighten it by providing advocacy services that offer personalized help when patients need it. If you need copay assistance, our funding team goes to work, connecting you with the third-party organizations that can help. We’re here for you every step of the way.

Products We Support

Programs


  • ACT10N logo

    With ACT10N, patients with factor X deficiency have access to a highly specialized infusion care program, complete with personal support, clinical care and monitoring.

  • REBUILD logo

    Physical therapy is key to comprehensive hemophilia management. REBUILD facilitates training and connections between hemophilia patients and their local physical therapists.

  • IMPACT logo

    A comprehensive in-home inhibitor management program, IMPACT helps families affected by hemophilia with inhibitor options, education and personal support.

Pieces of Interest

  • Can I Use Diplomat?

    Can I Use Diplomat?

    We provide benefits investigation and help verify your eligibility for our programs and services. Fill out a simple form and we’ll get in touch with you.
  • Hemophilia Financial Assistance

    Hemophilia Financial Assistance

    We help connect bleeding disorder patients with nonprofit, manufacturer-sponsored and third-party funding options to keep therapy affordable.
  • Hemophilia of North Carolina Educational Scholarship Program

    Hemophilia of North Carolina Educational Scholarship Program

    All bleeding disorder patients, siblings, caregivers or parents pursuing higher education or professional training are encouraged to apply.
  • It’s Always About Nate

    It’s Always About Nate

    The fourth in the “Nate” series, this children’s story explores how bleeding disorders affect parents’ and siblings’ lives too—and how a little compassion can go a long way.
  • The Great Inhibinator

    The Great Inhibinator

    By working through his feelings with his family, six-year-old Nate finds a way to feel powerful despite his inhibitor diagnoses.
  • StrapWrap®

    StrapWrap®

    Able to fasten to seatbelts, bag straps and bicycles, the StrapWrapⓇ keeps medical history and information secure and accessible to emergency responders.
  • Hemophilia Newsletter

    Hemophilia Newsletter

    Stay current on news, tips, stories, advancements and more from the hemophilia community. Available via email or print.
  • Kids Hemophilia Calendar Contest

    Kids Hemophilia Calendar Contest

    Children with bleeding disorders and their families are invited to submit artwork for this year’s calendar contest.
  • Be a Hero Mat

    Be a Hero Mat

    This mat provides a clean surface to help children learn to infuse at home, with clear instructions and colorful illustrations.

Featured Technology

A mobile health care application for patients with hemophilia and related bleeding disorders. The app helps patients conveniently track their personal infusion records and bleeding event history, as well as share important injury and treatment information with members of their health care team.

Learn more

From the Whole Health Blog

  • Far More Than an Adventure

    Far More Than an Adventure

    Blog

    April 17, 2017

    Eric Hill, chief operating officer at Diplomat Specialty Infusion Group, and his son traveled to Kenya to climb Mount Kilimanjaro. Far more than an adventure, their trip was dedicated to raising money for a nonprofit dedicated to assisting people living with hemophilia in developing countries.

  • Unbroken: How a Mother Finds Strength While Facing Her Sons’ Hemophilia

    Unbroken: How a Mother Finds Strength While Facing Her Sons’ Hemophilia

    Blog

    April 14, 2016

    Mother of two boys with hemophilia, June shares how their journey inspired her to pursue a passion for helping others.

Receive more information on what matters to you.

Twitter